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Description

It was previously reported that a small part of Trp produced 5-HT through tryptophan hydroxylase (TPH), whereas about 95% of Trp produced KYN through the catalysis of indolamine 2,3-dioxygenase (IDO) or tryptophan2,3-dioxygenase (TDO) (46)

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The DNA sequence of the D23A mutant was verified by DNA sequencing

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